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Estring Vaginal Ring

Talk to Your Doctor About Estring

Estring is a soft, flexible vaginal ring that is clinically proven to relieve moderate-to-severe painful sex, burning, itching, dryness, and painful urination caused by postmenopausal changes.

Estring gradually releases estrogen for 90 days at the site of pain, helping restore vaginal tissue to a healthier condition.

Having the conversation about moderate-to-severe vaginal symptoms after menopause can be uncomfortable, but it doesn’t need to be. If you want to talk to your doctor about possible treatment with Estring but you aren’t sure how to start, here are some tips to get the conversation going:

Download and print our Estring_Downloadable_Doctor_Discussion_Guide before your next appointment.

Talk to your doctor and see if Estring is right for you

If your doctor determines Estring is right for you, all that’s left to do is insert it, let it work, and then remove and replace with a new ring after 90 days if you and your doctor decide to continue treatment. Keep in mind that estrogen therapies such as Estring should be used only as long as needed. You and your doctor should talk regularly about whether you still need treatment with Estring.  Download and print our Estring insertion_and_Removal_Guide.

Estring FAQ’S

What is Estring?

Estring is a slightly opaque, soft, flexible vaginal ring with a center that contains 2 mg of estradiol (an estrogen hormone). It releases estradiol into the vagina in a consistent, stable manner for 90 days. Estring is indicated for use after menopause to treat moderate-to-severe vaginal itching, burning and dryness, painful intercourse, urinary urgency, and painful urination.

How do I store Estring?

Estring can be kept anywhere convenient, like your bathroom cabinet. It should be stored at room temperature between 59°F and 77°F (15°C and 25°C).

How long should I use Estring?

Estring contains the estrogen hormone estradiol. Therefore, Estring should be used only as long as needed. You and your doctor should talk regularly (for example, every 3 to 6 months) to see if you need to continue treatment.

Will I or my partner feel Estring?

Most women and their partners do not experience any discomfort with Estring in place, including during sex, so you don’t have to remove the ring before sex. However, if you choose to remove it, be sure to put it back in soon afterward.

If you take Estring out, rinse it in lukewarm (not hot) water before you put it back in. If you can feel it, Estring may be too low in your vagina. To push it in farther, simply use your finger. For more information on how to insert and remove Estring, watch our instructional video.

Can Estring be inserted too far?

No. Estring cannot be pushed too far up in the vagina or get lost. Estring will not go past the end of the vagina. The cervix (the narrow, lower end of the uterus) blocks Estring from going up any further. If you have any concerns or additional questions about inserting Estring, contact your doctor.

What if my Estring falls out?

No need to worry. It’s rare, but has been reported in cases of intense coughing or straining. If this happens, just rinse the ring with lukewarm water and reinsert it. Do not wash the ring in hot water.

How do I dispose of Estring?

Simply dispose of Estring in your regular wastebasket. Do not flush Estring down the toilet.

What are some side effects and risks of Estring?

Less serious but common side effects include:

  • Headache
  • Breast pain
  • Irregular vaginal bleeding or spotting
  • Stomach/abdominal cramps, bloating
  • Nausea and vomiting
  • Fluid retention
  • Vaginal yeast infection

Less common but serious side effects include:

  • Heart attack
  • Stroke
  • Blood clots
  • Dementia
  • Breast cancer
  • Cancer of the lining of the uterus (womb)
  • Cancer of the ovary
  • High blood pressure
  • High blood sugar
  • Gallbladder disease
  • Liver problems
  • Changes in your thyroid hormone levels
  • Enlargement of benign tumors of the uterus (“fibroids”)

Do not start using Estring if you:

  • Have unusual vaginal bleeding
  • Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause
  • Currently have or had certain cancers
  • Estrogens may increase the chance of getting certain types of cancers, including cancer of the breast or uterus. If you have or have had cancer, talk with your healthcare provider about whether you should use Estring
  • Had a stroke or heart attack
  • Currently have or had blood clots
  • Currently have or had liver problems
  • Have been diagnosed with a bleeding disorder
  • Are allergic to Estring or any of its ingredients (Please see the list of ingredients in the Patient and Prescribing Information)

Think you may be pregnant

  • Estring is not for pregnant women. If you think you may be pregnant, you should have a pregnancy test and know the results. Do not use Estring if the test is positive and talk to your healthcare provider

What are other things to tell my doctor?

Call your healthcare provider if you get any of the following warning signs:

  • New breast lumps
  • Unusual vaginal bleeding
  • Changes in vision or speech
  • Sudden new severe headaches
  • Severe pains in your chest or legs with or without shortness of breath, weakness, and fatigue
  • Memory loss or confusion

Before starting Estring, tell your doctor or healthcare professional:

  • If you have unusual vaginal bleeding. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find out the cause
  • If you have other medical conditions. Your healthcare professional may need to check you more carefully if you have certain conditions, such as asthma (wheezing), epilepsy (seizures), diabetes, migraine, endometriosis, lupus, angioedema (swelling of face and tongue), or problems with your heart, liver, thyroid, kidneys, or have high calcium levels in your blood
  • If you are going to have any surgery or will be on bed rest. Your healthcare provider will let you know if you need to stop using Estring
  • If you are breastfeeding. The hormone in Estring can pass into your breast milk
  • About all the medicines you take, such as prescription and nonprescription medicines, vitamins, and herbal supplements. Some medicines may affect how Estring works. Estring may also affect how your other medicines work

Estring may provide relief for your moderate-to-severe vaginal symptoms after menopause. Ask your doctor if it’s right for you.

To learn more visit www.estring.com.

To learn more about the gynecologic services offered by our OB/GYN doctors in Pinehurst and Sanford, NC, please contact us today at 910-295-0290. We’d be happy to help you set up an appointment. If you are a current patient of Pinehurst Surgical, you may also request an appointment online using your My Patient Page.

Pinehurst Surgical is a multi-specialty clinic comprised of ten specialty centers located in a state-of-the-art surgical facility in Pinehurst, NC. Our OB GYN specialists offer a selection of medical services for gynecological issues at our Pinehurst and Sanford clinical offices, serving patients in Southern Pines, Fayetteville, Red Springs, Asheboro and all surrounding areas throughout North Carolina, South Carolina, and beyond.

At Pinehurst Surgical, each of our surgeons in Pinehurst, Sanford, Troy, Rockingham, Laurinburg and Raeford, NC is truly a specialist in his or her field. So whether you’re coming in for a routine checkup or a major surgery, you can feel confident knowing that your problem will be treated in the most thoughtful, dedicated manner possible.