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Premarin Vaginal Cream

How Premarin Vaginal Cream works:

For many menopausal women, changes to the vagina can cause pain during intercourse, called dyspareunia.

Premarin Vaginal Cream is clinically proven to relieve moderate to severe painful intercourse caused by menopausal changes. It works by delivering estrogens directly to the source of the pain, which helps rebuild vaginal tissue and make intercourse more comfortable.

How It Works


How to Apply

Starting to treat the symptoms of moderate to severe painful intercourse takes just a few steps.


Frequently Asked Questions:

How common are vaginal symptoms after menopause?

Up to 40% of postmenopausal women experience vaginal atrophy, and painful intercourse is a common symptom. While it’s not usually discussed as openly as hot flashes and night sweats, you’re certainly not the only one.

How can I tell if it’s vaginal atrophy?

With vulvar and vaginal atrophy (VVA), you may experience dryness, burning, and itching in and around the vagina. And having intercourse may be painful. If you’re experiencing any of these symptoms, make an appointment to see your doctor. There are prescription treatments that may be able to help. To prepare for your appointment, print your Doctor-Discussion-Guide.

Do vaginal symptoms ever go away?

Vaginal symptoms like moderate to severe painful intercourse are unlikely to go away on their own and may even worsen over time. Talk to your doctor about whether Premarin® (conjugated estrogens) Vaginal Cream may be right for you.

Can I just use one of those “personal lubricants”?

Over-the-counter lubricants may give you some temporary relief from your symptoms. But they weren’t designed to do what a prescription treatment can. Premarin® (conjugated estrogens) Vaginal Cream provides estrogen to help rebuild vaginal tissue and make intercourse more comfortable. Learn more about how Premarin Vaginal Cream works.

How should I bring this up with my healthcare provider?

Talking with your healthcare provider can be your first step in finding relief. Your doctor can properly diagnose your condition after a physical exam and a brief conversation. Watch the Start the Discussion video below or download the  Doctor-Discussion-Guide to help get the conversation started.

How often do I need to use Premarin Vaginal Cream?

You should apply the cream in accordance with your prescribed treatment schedule. It can be applied at any time of day that’s convenient for you.

To treat moderate to severe painful intercourse due to menopause, Premarin® (conjugated estrogens) Vaginal Cream can be applied twice a week (for example on the twice-a-week regimen, you might choose Monday and Thursday evening) or in a cyclic regimen of 21 days of therapy, followed by 7 days off therapy, using a 0.5 g dose.

To treat vulvar and vaginal atrophy (VVA), Premarin Vaginal Cream should be applied in a cyclic regimen of 21 days on therapy, followed by 7 days off therapy. Generally, women should be started at the 0.5 g dosage strength. Dosage adjustments (0.5 to 2 g) may be made based on individual response.

Estrogens should be used at the lowest effective dose, for the shortest duration consistent with treatment goals and risks for the individual woman. You and your doctor should talk regularly to decide how long you need treatment.

How long until I start to feel a difference with painful intercourse?

Sticking with your treatment plan is key to feeling relief. In a clinical study, patients taking Premarin Vaginal Cream felt significant relief of moderate to severe painful intercourse due to menopause at 12 weeks. Individual results may vary.

To learn more about the gynecologic services offered by our OB/GYN doctors in Pinehurst and Sanford, NC, please contact us today at 910-295-0290. We’d be happy to help you set up an appointment. If you are a current patient of Pinehurst Surgical, you may also request an appointment online using your My Patient Page.

Pinehurst Surgical is a multi-specialty clinic comprised of ten specialty centers located in a state-of-the-art surgical facility in Pinehurst, NC. Our OB GYN specialists offer a selection of medical services for gynecological issues at our Pinehurst and Sanford clinical offices, serving patients in Southern Pines, Fayetteville, Red Springs, Asheboro and all surrounding areas throughout North Carolina, South Carolina, and beyond.

At Pinehurst Surgical, each of our surgeons in Pinehurst, Sanford, Troy, Rockingham, Laurinburg and Raeford, NC is truly a specialist in his or her field. So whether you’re coming in for a routine checkup or a major surgery, you can feel confident knowing that your problem will be treated in the most thoughtful, dedicated manner possible.